Description
Our structure-based drug design (SBDD) services are supported by medicinal chemistry, computer-aided drug design (CADD), and protein production services. Our structural biology experts, with proven experience in biophysical characterization, X-ray structure determination, and in silico docking analysis, have determined more than 250 high-resolution crystal structures of a variety of targets, advancing drug discovery and development efforts for our clients.
Services include:
- Biophysical Characterization (thermal shift assays, SPR analysis, fluorescence polarization assays, isothermal titration calorimetry, and dynamic light scattering)
- SPR Binding Analysis (for structure-function analysis, screening, and characterization of drug candidates, screening and rank ordering of protein-protein and drug-protein interactions, measurement of interaction kinetics and affinity, and interactant concentration determination)
- Protein Crystallization
- Structure Determination by X-Ray Crystallography and Cryo-EM
- In Silico Drug Design/CADD